Graphical Launcher for Linux
Dungeons & Dragons Online uses virtually an identical launcher to Lord of the Rings Online (the game LotROLinux was designed for), after a small modification this launcher can now launch Dungeons & Dragons Online on a Linux system.
LotRO works very well under wine, with just a few adjustments needed to wine's registry and the games UserPreferences.ini file. Details of these adjustments can be found at the wine AppDB page for the Lord of the Rings Online or the How-To's on this site, one dealing with installing and patching via Linux and the other via Windows on this site. Though I do not know if the CLI launcher works correctly with DDO. Since the LotRO engine and DDO engine are similar I would expect the options that need tweaking to be the same.
Download the latest version, note this is a source tarball, to compile it you need the mono compiler installed, additional information is in the README file.
